The E-Mu 0404 PCIe has low-latency audio for better use with live performance. This card has audio in, out, and MIDI in and out. It has PDI-F optical, but I don't tend to use this.

I've been using the following drivers/application for a few years without known problems:

• Sound drivers EmuPMX_PCDrv_US_2_30_00.exe
• Sound application (mixer console) EmuPMX_PCApp_US_2_20_00.exe

Drivers, etc.: http://emu.com/index.php/support-e-mu-0404-pcie

For apps to send sound, they need to send on ASIO channels 31/32.